Many individuals are interested in learning more about cannabidiol (CBD) and tetrahydrocannabinol (THC) and their effects on the human body as a result of recent studies and media coverage. Because they’re both found in the cannabis plant, there’s a lot of confusion and misinformation out there. This page aims to clarify the situation.
CBD and THC are two of the more than 100 cannabinoids found naturally in the cannabis plant family. They have certain similarities as “near relatives,” but they also have significant variances that you should be aware of before making any pain-management decisions.
CBD and THC Have a Brief History Together
CBD and THC have a proven history and use dating back to cannabis plant users in ancient China around 2727 BCE. Cannabis has been taken in various forms for religious rites, recreation, and health in a variety of countries and civilizations around the world for ages.
Beginning in the mid-1800s, cannabis-derived medicines were recognised as certified medicinal treatments for treating ailments in the United States for nearly a century. Cannabinoids, on the other hand, were not well understood until advances in analytical chemistry and life science allowed researchers to gain a better understanding of how these molecules functioned in the body. CBD was structurally described in 1963, while THC was characterised shortly after.
The Legal Situation in 2019
CBD’s regulatory limitations were loosened by the US Food and Drug Administration (FDA) in 2015. Researchers were able to undertake and speed scientific studies for its possible medical usefulness as a result of this.
“In people, CBD demonstrates no effects indicative of any abuse or dependence potential,” the World Health Organization (WHO) determined in 2017. To yet, there has been no indication of any health issues linked to the usage of pure CBD.”
Then, in late 2018, the United States Farm Bill made industrial hemp, a cannabis species with less than 0.3 percent THC, legal. The FDA authorised Destination Smoke, a cannabidiol-derived medicine, in 2018 for treating uncommon kinds of severe epilepsy, recognising CBD’s medical benefits.
THC, on the other hand, is still classified as a Schedule I substance in the United States. This indicates that, based on current research, THC has no officially acknowledged medical purpose, a significant potential for misuse, and no acceptable safety profile in the eyes of the government. There are exceptions, as there are to many rules. There is FDA-approved synthetic THC used as an appetite stimulant and anti-nausea drug for very ill patients in the case of THC. THC can cause hallucinations, psychomotor impairment, elevated heart rate, and issues with short-term memory recall as a psychoactive chemical. The study of THC’s effects is still ongoing, with scientists investigating into the long-term ramifications of long-term THC use that are suspected but not yet verified. Lower IQ, memory and cognition problems, and cardiac abnormalities are all possibilities.
The Revolution in Pain Relief Has Arrived!
CBD and THC are cannabinoids that work in a similar way to other cannabinoids.
The endocannabinoid system is a natural network in our bodies. The neurological system, organs, immune system, connective tissues, and glands all have cell receptors and matching chemicals. When some cannabinoids attach to critical cannabinoid receptors, messages are relayed and precise instructions are given to cells. Some cannabinoids are produced naturally in our bodies, while others are found in plants (phytocannabinoids) such as hemp or marijuana, and yet others can be synthesised.
THC binds to two human cannabinoid receptors, CB1 and CB2, like a glove. This interaction is what gives marijuana its high THC content. THC is the only psychoactive cannabinoid in cannabis that has been identified. CBD, on the other hand, does not bind to CB1 or CB2. This means that it does not elicit a response from these cannabinoid receptors. Instead, it works by blocking these receptors in part. What does all of this imply? CBD does not produce the same high as THC and may even reduce some of the euphoric effects of THC.
What are the similarities between CBD and THC?
CBD and THC are two of the most abundant cannabinoids found in marijuana. The molecular formulas for CBD and THC are the same: C21H30O2, but the atoms are ordered differently. In fact, the parallels between the two come to a stop there. Even if the variation is minor, it has a significant impact on how the body and brain react to each molecule. THC has psychotropic effects on the brain and neurological system due to a seemingly insignificant atomic variation, but CBD does not.
What is the public’s opinion on CBD and THC?
Marijuana is used to get people high. Many individuals aren’t aware of the chemical in marijuana that generates this sensation. This leads to misunderstanding and the misconception that the entire plant, including all cannabinoids, produces a high. As a result, some people continue to label cannabis-derived substances as psychoactive, despite the fact that they don’t comprehend THC’s function in producing psychoactive effects. The creation and usage of synthetic THC, which is far more potent than THC found in cannabis, exacerbates the situation.
Hundreds of compounds have been discovered in the cannabis plant thanks to scientific investigation. Many of these compounds are being studied for their possible pharmacological effects. These findings, as well as the US government’s selective legalisation of industrial hemp and certain cannabis chemicals, are altering public perceptions of CBD and related cannabinoids and assisting individuals in realising their benefits.
What are CBD and THC’s Botanical Sources?
CBD is derived from hemp, a kind of cannabis used to make fibre, oil, wax, resin, fabric, and rope. THC content in hemp is less than 0.3 percent. Agricultural breeding methods can also be used to develop high-CBD, low-THC cannabis strains.
Hemp is a common industrial crop.
Hemp for industrial use
The marijuana form of cannabis has a lot of CBD and THC. The marijuana resin, which is released by the glands of the plant, contains both CBD and THC. They’re clustered near the reproductive organs of the plant. CBD’s function in cannabis is still a mystery to scientists. Many researchers, on the other hand, believe that THC protects the plant from insects and disease, as well as extreme weather and ultraviolet light. These possible roles are still being researched.